Michele Anacondia is a criminal on the fringes of the Apulian mafia, whose wife pushes him to achieve more. Their only son dies in an ambush and the man kills half of a rival gang. The boss promotes him, and when his enemies set fire to his residence, he takes refuge with Michele and his wife. Michele is not satisfied: he kills the godfather and takes command of the Sacra Corona. But his thirst for blood will plunge him into madness.